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One very small study found that people who used semaglutide had lower B12 levels, but these patients also had bariatric surgery prior to using semaglutideso its hard to say if using semaglutide would lead to a B12 deficiency, requiring additional B12

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Oral Supplements Some online vendors market oral BPC-157 as a dietary supplement for gut healing or joint support. There is no evidence supporting its effective absorption when taken orally

[1] The American Diabetes Association (ADA) primarily recommends B12 monitoring for patients on long-term metformin therapy rather than for those on GLP-1/GIP receptor agonists