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Based on these data, pivotal phase 3 trials comparing icotrokinra with placebo in participants aged 12 years and older with moderate-to-severe plaque psoriasis [ICONIC-LEAD (NCT06095115)] and plaque psoriasis involving difficult-to-treat high-impact sites including scalp, genitals, and hands/feet [ICONIC-TOTAL (NCT06095102)], have been initiated (Table 3)

Coconut oil, for example, is rich in lauric acid (C12), which is sometimes classified as an MCT but is metabolized more like a longer-chain fat

Typical Dosage: Frequency and amount are determined by patient needs and healthcare providers

Apostolopoulos, V., Bojarska, J., Chai, T

Antioxidant metabolism The presence of the antioxidant system can prevent the infinite expansion of lipid peroxidation, which is a core step in impeding ferroptosis

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