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These symptoms typically worsen during periods of rest or inactivity, particularly in the evening and at night, leading to sleep disturbances and a significant impact on quality of life

10.1038/srep33052 47 ZengH.JiangY.ChenP.FanX.LiD.LiuA.et al (2013)

(May 2019)

If there was significant heterogeneity, an increased quantity of included studies was necessary

Moreover, the HIV infection also causes mild neurocognitive disorder and demyelinating neuropathy with motor and sensory impairments

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