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1c) serves as a control to ensure that equal amount of D2R was present in each sample and that the differences in co-immunoprecipitation of DAT were due to changes in the degree of D2R-DAT interaction, rather than antibody artifacts

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Further, AC was shown to interfere with the catalytic cavity of cyclo-oxygenase-2 (COX-2) and hinder the production of prostaglandin E2 (PGE2), with reduced impact on COX-1 activity in free fatty acid-treated RAW 264.7 and THP-1 macrophage cells (Ma et al