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Insulin resistant cellsparticularly those of muscle and fat tissueno longer use insulin efficiently to remove glucose from the bloodstream, which predisposes to diabetes and high blood pressure (Reaven 1988

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Confirm the active substance is not currently on the FDA's "do not compound" list or has had its shortage designation removed

It has been used in numerous clinical trials and is considered the gold standard for identifying cerebral folate deficiency due to autoimmunity