doi:10.1093/ajcn/74.2.233
Tretinoin, a prescription vitamin A derivative, has been called the most potent and certainly the most widely investigated retinoid for photoaging therapy by researchers in a 2006 review.49 And a more recent 2022 review notes that studies on tretinoin consistently find it to be efficacious in improving [the] clinical appearance of photoaging.50 And many nonprescription ingredients, like niacinamide (for melasma),51 vitamin C (for wrinkles),52 and hyaluronic acid (for dry skin), have demonstrated positive outcomes in studies.53 Some of our favorite online dermatology options that weve reviewed are Curology, Agency, Prose, and Musely
Linking mitochondrial dynamics, cristae remodeling and supercomplex formation: how mitochondrial structure can regulate bioenergetics
For skincare brands, this translates to products that actively repair existing damage while preventing future deterioration
If you are deficient in B12, a course of injections or high dose oral supplementation may be advised
At 15% and beyond, metabolic changes approach what bariatric surgery produces