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Alpha-lipoic acid (ALA) supplements Proponents of the antioxidant alpha-lipoic acid (ALA) claim several health benefits, including that it can help adults with type 2 diabetes with weight loss and lower blood sugar levels for adults, as well as treat nerve pain and lower cholesterol

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Several neuronal morphological studies also reported a reduction in synapse number and synaptic signaling proteins in the PFC of depressed patients through electron microscopy (Kang et al., 2012)