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Patients preferring minimal interaction may find the model more intensive than needed
10.1016/j.tibs.2010.05.003 229 XiangL.MouJ.ShaoB.WeiY.LiangH.TakanoN.et al (2019)
Researchers conducting dose-response studies or pilot experiments can reduce costs by starting with smaller batch sizes a single 5mg vial supports 50 doses at 100mcg each, sufficient for initial titration phases before committing to larger orders
Combined treatment with DCA and metformin significantly increased ROS generation, disrupted mitochondrial membrane potential, and activated caspase-dependent cell death pathways, while also reducing lactate production, indicating suppression of aerobic glycolysis
Ethics declarations Conflict of interest The authors declared no potential conflicts of interest with respect to the research, authorship, and publication of this article
