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The crude material was purified by automated flash column chromatography on silica via gradient elution, from 100% dichloromethane to 1% methanol in dichloromethane to produce SS(NHS-CM) 2 (979 mg, 79%) as an off-white foamy solid

Oxidative stress plays a critical role in its pathogenesis, as ROS and RNS produced during inflammation stimulate melanocyte proliferation and melanin synthesis, primarily via upregulation of TYR activity 130

| Antioxidant effect of L-carnitine and its short chain esters: relevance for the protection from oxidative stress related cardiovascular damage

In addition to Glutathione, it contains a collagen builder of aloe vera and vitamin C helps to inhibit collagen breakdown, retaining skin elasticity, volume, and moisture