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L., Jensen, C
Other candidates for dual and triple combination therapies have focused on glucagon receptor agonism with its potential specific added effects on the liver
The most commonly reported adverse effects are gastrointestinal in nature and include: Nausea (particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects are generally dose-dependent and tend to be most pronounced during the initial weeks of treatment when the dose is being gradually increased
REP reports consulting fees from Bayer AG, Corcept Therapeutics, Dexcom, Hanmi Pharmaceutical Co., Merck, Novo Nordisk, Pfizer, Sanofi, Scohia Pharma Inc., and Sun Pharmaceutical Industries