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Novik AV, Protsenko SA, Baldueva IA, Berstein LM, Anisimov VN, Zhuk IN, et al

This is mechanistically different from injecting recombinant GH itself: a GHRH agonist raises GH indirectly, through the pituitary, so the output remains at least partly subject to the axiss normal regulation including negative feedback from IGF-1 and somatostatin

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Sachar, D