Certain women may have extra skin that doesnt fully retract after giving birth, particularly if they have had multiples or have significantly gained weight
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Severe Gastrointestinal Diseases and Pancreatitis History Active or severe inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, can worsen with tirzepatide initiation due to slowed gastric motility and altered gut hormone signaling
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They also may suppress appetite, although not their intended use
For weight management, NICE has appraised several licensed medicines that are available through NHS pathways or regulated private clinics: Semaglutide (Wegovy) NICE Technology Appraisal TA875 recommends semaglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when used within a specialist weight management service