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(Kidney International 2022): Route : Chronic infusion in mice Models : STZ-induced type 1 diabetes and db/db type 2 diabetes Duration : Multiple weeks of treatment Outcomes : Reversed proteinuria, attenuated glomerular hypertrophy, mitigated podocyte damage, ameliorated fibrotic lesions Control : Scrambled-sequence KP6 showed no therapeutic effect Klotho Protein for Cognitive Enhancement# For the full KL1 domain (not KP1/KP6 peptides): In Castner et al