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regeneration of glutamate from 5-oxoproline by 5-oxoprolinase requires hydrolysis of ATP, and resynthesis of glutathione requires another two molecules of ATP

Abstract Enteroendocrine cells lining the gut epithelium constitute the largest endocrine organ in the body and secrete over 20 different hormones in response to cues from ingested foods and changes in nutritional status

Furthermore, tissue and cell lysates, particularly from bronchiolar epithelium which is a major site of CAT expression in healthy lungs, are highly relevant for investigating CATs contribution to lung pathology, including that observed in CF (Odajima et al., 2010)

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For those with stage 5 CKD that is managed with hemodialysis or peritoneal dialysis, a diet providing 1.01.2 g/kg/day of protein is recommended