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Nagafuku, M

Although corticosteroids are not generally recommended for the treatment of rosacea [6], because the level of inflammation in this patient was high, and similar to levels seen in patients with rosacea fulminans, it was decided that the initial course of treatment should consist of azithromycin 500 mg three times weekly in combination with prednisolone (initially 30 mg once daily and then gradually reduced and stopped)

But medical literature evidence suggests these same pathways may interfere with key skin functions by: Slowing fibroblast activity, reducing the production of structural proteins like collagen and elastin Decreasing cell turnover, leading to dullness and slower skin renewal Compromising the skin barrier, increasing water loss and sensitivity to environmental damage The result

target the 8.09.5 range

This decision is important because MFDS accepted GLP-1 as a valid biomarker, unlike EFSAs more cautious approach

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