Pflugers Arch 444:579585 Serman Y, Fuentealba RA, Pasten C, Rocco J, Ko BCB, Carrion F, Irarrazabal CE (2019) Emerging new role of NFAT5 in inducible nitric oxide synthase in response to hypoxia in mouse embryonic fibroblast cells
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Abstract Rheumatoid arthritis (RA) is a complex autoimmune disease driven by dysregulated epigenetic mechanisms, with histone deacetylases (HDACs) playing isoform-specific pathogenic or protective roles by modulating histone acetylation, immune function, and bone metabolism
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In the current investigation, we specifically implemented the Reporting Odds Ratio (ROR) methodology to detect adverse reaction signals, utilizing both the System Organ Class (SOC) and Preferred Term (PT) classifications for the target pharmacological agents
