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Further research in this area may help to identify more precise dietary interventions that can ultimately improve outcomes for individuals at risk of developing obesity-associated cancers

10.1016/j.neurobiolaging.2014.10.012 157 HonjoY.KanekoS.ItoH.HoribeT.NagashimaM.NakamuraM.et al

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While metformin's mechanism(s) of action remain controversial, current evidence indicates that metformin's most important effect in treating diabetes is to lower the hepatic production of glucose (as summarized in the top left box)