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AFUs tend to provide a more accurate quantity of how many live, active microorganisms each serving of a supplement contains

Study selection and eligibility criteria We included randomized or unrandomized controlled trials, single-arm trials, and RWE studies evaluating AID in non-pregnant patients with type 2 diabetes requiring insulin therapy

Pasquier F, Pla R, Bosquet L, Sauvet F, Nedelec M, Consortium DD

PMID: 14523363

No significant safety complaints or adverse event reports were found in public records as of March 2026.

54 However, these studies were observational or post hoc analyses, and dementia was not the primary outcome