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Acknowledgements The authors thank Ccile Desjobert, Ph.D and Marielle Romet, Ph.D (Synergy Pharm) who provided medical writing assistance funded by Laboratoires dermatologiques Avne

There was a higher level of leptin mRNA expression in the mesenteric white adipose tissue (mWAT) of patients with IBD compared to the control group suggesting that leptin may play a role in the inflammatory process by increasing the expression of mesenteric TNF (290)

In both groups BMI is not significant predictor of GSH

To preserve long-term benefits, its crucial to combine GLP-1 medications with lasting lifestyle adjustments

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

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