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BioMed Pharmacother (2017) 89:88793

The association between second-line oral antihyperglycemic medication on types of dementia in type 2 diabetes: a nationwide real-world longitudinal study

Nauck MA, Ritzel R, Maubach J, Bsing M, Frystsyk J, Holst JJ, Lck R, Becker T, Klempnauer J, Schmiegel W

Later some batches showing around 30 % release in 24 hrs are found to exhibit substantial release over 72 hrs

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Other factors, such as hydration status, initial serum creatinine levels (an indicator of kidney function), and levels of calcium, phosphate, and bicarbonate in the body, can also be predictors