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After 6 months, the rats were sacrificed, the blood sample collected and the kidneys harvested for evaluation of biochemical analytes, genes expression, and histopathological changes

In db/db mice, previous studies found that AMPK activation could reduce ROS production and increase mitochondrial biogenesis and ETC activity to alleviate kidney damage in diabetic models[150, 151]

It supports muscle maintenance, promotes satiety, and regulates metabolism

Many people associate metabolism with calories burned in a day

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