BACE1, Beta-site Amyloid Precursor Protein Cleaving Enzyme 1
Interestingly, the infiltration of Th1 and Th17 cells into the CNS, as well as the secretion of cytokines by CD4+ T cells, could also be initiated by ferroptotic neurons, which were induced by over-expression of ACSL4 (a regulator of PUFA-PLs synthesis) (58)
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Lycopene is a polyphenol, or plant compound, that has been linked with one type of Tomato products provide A Diets rich in beta-carotene Further human-based research is needed to explore the possible roles of lycopene and beta-carotene in preventing or treating cancer
Furthermore, pre-synaptic and post-synaptic proteins, synaptophysin and PSD-95, which reflect synaptic disruption [122], were upregulated, neuronal excitability normalized, and intracellular calcium, a key regulator in metabolic dysfunction and progressive neuronal loss [123], was modulated [121]
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