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doi: 10.1038/s12276-022-00725-z 17 FolchJLeesMSloane StanleyGH

Redox homeostasis and immune alterations in coronavirus Disease-19

As a polyspecific transporter, OCTN1 is capable of transporting a variety of organic cations and zwitterions (e.g., tetraethylammonium, acetylcholine, and ergothioneine) and is also involved in the transport of certain drugs

ER activation inhibits hepatic macrophage M1 polarization, while ER knockdown promoted hepatic steatosis, M1 macrophage infiltration, and fibrogenesis in female mice (112)

This then results in a more contoured, slimmer and refined appearance in the treated area

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