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Mechanistically, this effect is attributed to the stimulation of lipolysis, supported by the upregulation of lipolytic enzyme genes Atgl and Hsl, alongside the downregulation of adipogenesis-related genes Fabp4 and Dgat

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MOTS-c has a plasma half-life of approximately 2 hours, but its metabolic effects persist for 68 hours due to downstream signalling cascades

Higher heart rate variability is generally considered a positive reflection of autonomic balance and stress resilience

Depression Depression is another major psychiatric disease

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