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You must inform your healthcare provider if you have the following: Type 1 diabetes, because tirzepatide is not a substitute for insulin

Safety when exploring alternatives Each treatment has different safety points and dosing plans

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However, given its potential effects on recovery and performance, it could attract regulatory attention in the future

Particularly, the reduction of GLP-1 release over time has been an observed feature of T2DM development, as GLP-1 reduces glucagon secretion and hepatic gluconeogenesis while promoting insulin secretion, thereby effectively minimizing hyperglycemia [106]

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