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100% of participants experienced improved wrinkle appearance

A meaningful change in PF score was achieved by most patients (77.3%) taking oral semaglutide 25 mg versus those taking placebo (42.9%)

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[218] Patients should work closely with their healthcare providers to determine the most appropriate dosing frequency based on their specific circumstances

doi: 10.3389/fonc.2019.00348 76 IsvoranuGSurcelMMunteanuANBratuOGIonitaRaduFNeaguMTet al

These results suggested that GLP-1 expression was gradually decreased in CM, and also revealed that although the protein expression of GLP-1R was upregulated after NTG stimulation, the amount of GLP-1Rs that can be activated was decreased, so the activity of GLP-1R in the TNC in CM model was actually inhibited