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Its a catastrophic but surprisingly common issue in research settings

BugianesiEManziniPD'AnticoSVanniELongoFLeoneNet al

10.1016/j.atherosclerosis.2019.11.013 Atherosclerosis

AT-II is the most studied stimulus of the upregulation of NADPH oxidase, but ET-1 and urotensin II may also participate to the activation of NADPH oxidase, thereby resulting in increased ROS