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Transferrin receptor 1 (TfR1), a well-known regulator of cellular iron that internalizes the transferrin-bound iron, plays a significant role in ferroptosis, and ROS induction has been shown to enhance TfR1 protein levels and serves as a marker of ferroptosis 8

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doi: 10.1186/s12974-019-1564-7 26 BrusciaE

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After cooling the product to room temperature, the remaining thionyl chloride was removed by repeated additions of toluene under vacuum conditions

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