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doi: 10.3389/fimmu.2025.1578940 Received 18 February 2025 Accepted 24 March 2025 Published 10 April 2025 Volume 16 - 2025 Edited by Fabrizio Fontana, University of Milan, Italy Reviewed by Bjrn Steen Sklhegg, University of Oslo, Norway Josephine Anthony, Meenakshi Academy of Higher Education and Research, India Updates Copyright 2025 Fang, Gao, Jiang, Li and Li

EC 1.11.1.9

For both ubiquitylome and proteome analysis, carbamidomethylation (C) was used as a fixed modification

(A) Structure of HGF consisting of a -chain (69 kDa) including four Kringle domains and a -chain (43 kDa) including a serine proteinase homology (SPH) domain, linked by disulfide bonds (S)

Always swirl gently or allow passive dissolution

Lifestyle changes like reducing alcohol, quitting smoking, and sleeping well