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When initiating pharmacotherapy for arterial hypertension, the guideline Management of arterial hypertension (version 2018) of the German Society for Cardiology recommends a double combination, preferably as an SPC (single-pill combination)

In the second subgroup (ALC add-on vs the same background drug), Gavrilova et al 19 observed AEs in 35% with ALC add-on versus 45% with antidepressant alone, and Ramezani et al 20 reported AEs in three patients (1 in ALC + sertraline, 2 in sertraline + placebo)

Third-party testing by independent laboratories provides an additional layer of verification

By enhancing myocardial contractility, GLP-1 contributes to efficient cardiac function [42]

Yes, if theyre made with clinically validated ingredients

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