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Bioactive metal-containing nanomaterials for ferroptotic cancer therapy

This review emphasizes the mechanisms by which polyphenols are metabolized by gut microbiota, while exploring potential factors that limit the polyphenols effects, including bioavailability, metabolic factors, dietary content, and individual variability

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Effect on Transporter Protein Expression and Function For delivery via a transporter-mediated brain targeting approach, (pro)drugs and nanocarriers should possess high affinity to the transporter, which can affect the passage of physiologically important transporter substrates (210)

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