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Octreoscan may be useful to identify patients with active GO (106), but its role in clinical practice is limited, also in view of its high cost

For the mediation analysis on the histology endpoints evaluating change in body weight as mediator, data were based on complete-case on-treatment measurements to evaluate the mechanistic action of semaglutide in MASH (hence, data outside the on-treatment observation period were excluded)

Baseline kidney-related features of enrolled patients were balanced among treatment groups, with a mean eGFR of 81.3 ml/min/1.73 m 2 and UACR of 15 mg/g [49]

Semaglutide, known by brand names like Ozempic and Wegovy, is a GLP-1 (glucagon-like peptide-1) receptor agonist

Some of them affect children (degenerations with early onset, such as Friedreichs ataxia, injuries, and tumors in children)

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