We therefore hypothesized that supplementing BHB through a ketogenic diet consisting of a 4:1 ratio of fat to proteins and carbohydrates 42,43 could reprogram the metabolism of CD4 + T cells, thereby increasing their functionality in severe pulmonary viral infections
doi: 10.3389/fphar.2023.1191290 Received 22 March 2023 Accepted 28 July 2023 Published 08 August 2023 Volume 14 - 2023 Edited by Yusof Kamisah, Universiti Kebangaan Malaysia, Malaysia Reviewed by Patrick Orlando, Marche Polytechnic University, Italy Hana Rauchov, Academy of Sciences of the Czech Republic (ASCR), Czechia Iain Hargreaves, Liverpool John Moores University, United Kingdom Updates Copyright 2023 Dabbaghi Varnousfaderani, Musazadeh, Ghalichi, Kavyani, Razmjouei, Faghfouri, Ahrabi, Seyyed Shoura and Dehghan
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This decline is closely correlated with the loss of tissue regenerative capacity, increased inflammation, and accelerated skin aging
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