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doi: 10.1038/nrm3904 18 WangZWangWLuoQSongG

Nat Rev Drug Discov 19(9):609633

Photoaged skin shows a variety of age-associated clinical alterations, including deep wrinkles, discoloration, and irregular pigmentation

Since serum B12 concentrations do not always mirror the clinical picture, this marker is not optimally suited to monitor the effect of treatment, although it can help uncover a lack of patient compliance and malabsorption of oral B12 treatment

We thus tested the activity of alkaline phosphatase PhoA in different E

The team found that long-term treatmentmeaning six courses over 3 yearsresulted in numerous benefits, including: Patients also had lower rates of mortality than those in the control group who received basic therapy but no epitalon