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Description

The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person

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Nguyen T, Yang CS, Pickett CB (2004) The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress

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At a base level things like alcohol and tobacco or a meat rich diet can increase oxidative stress

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JAMA Netw Open 8, e2457349 (2025)

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