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Understanding neurodegeneration after traumatic brain injury: from mechanisms to clinical trials in dementia
Histopathological changes in cerebellar neuronal structure, such as loss of Purkinje cells (PCs), have been discovered in the postmortem brains of many ASD patients
rodentium was similar in both Pink1-KO mice and their littermate controls, however, the immune activation response was varied ( As mentioned, a pro-inflammatory state is required to recruit peripheral immune cells into the brain parenchyma, and dysregulation within this process can promote neurodegeneration (Scheld et al., 2016)