The risk of acute deterioration in retinopathy from rapid glycaemic control has a longstanding evidentiary basis but is not incretin therapy specific and should not dissuade against choosing these agents
For type 2 diabetes management , NICE guidance (NG28) recommends GLP-1 agonists as second- or third-line therapy when metformin and other oral agents provide inadequate glycaemic control, or as an alternative to insulin in appropriate patients
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Consistent use of dietary strategies and lifestyle modifications speeds this adjustment
It enhances the secretion of insulin and glucagon-like peptide-1 (GLP-1) and reduces glucagon secretion
While they may not deliver instant results like some synthetic treatments, their ability to restore balance, reduce inflammation, and improve the scalps foundational health gives them a lasting edge