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However, their clinical application remains challenging due to metabolic heterogeneity, compensatory pathway activation, and immunosuppressive effects

Further research is needed to fully elucidate the effects of IFP on breast cancer metastasis as well as the mechanisms governing pressure-induced responses

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Upon binding of a second equivalent of GSH into a highly energetic intermediate, the oxidized product GSSG is formed, and a ruthenium diamine complex generated

Previous studies have reported that overexpression of conventional Gsh1/Gsh2 pathway improved production of intracellular GSH along with accumulation of intermediate -GC which increased significantly when amino acid precursors were added [21]

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