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Additionally, a meta-analysis of multiple randomized, controlled trials confirmed that tesamorelin treatment significantly lowered visceral fat area and trunk fat, reduced hepatic fat, and was associated with a statistically significant increase in lean body mass, supporting its clinical effect on fat distribution and muscle preservation

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By aligning choices of anti-obesity drug with their specific mechanism of action towards patient specific factors, better treatment responses can be achieved (75)

Common examples include Ozempic, Wegovy, and Mounjaro

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