Because B12 is water-soluble, excess is excreted by the body
Common B12 deficiency symptoms include fatigue, anxiety, depression, poor memory, confusion, brain fog, tingling or numbness in the extremities, zings or zapping feelings in the extremities, anemia, shortness of breath, muscle weakness, irritability, tender calves, pale complexion and more
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If you need a 1 mg dose, you would draw 0.1 mL (or 10 units on an insulin syringe)
In the presence of excess oxygen methylcobalamin is photolyzed at a rapid rate to yield aquocobalamin and formaldehyde as the major products