Although PBM is considered a low-risk therapy, prolonged and repeated intra-cavitary irradiation warrants vigilance regarding potential side effects, such as cumulative effects of low-grade thermal injury or unintended biological modulation of normal chondrocytes and synovial cells (63)
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Nat Protoc 4:11841191 Germain PL, Lun A, Garcia Meixide C, Macnair W, Robinson MD (2021) Doublet identification in single-cell sequencing data using scDblFinder
10.1186/s12974-019-1434-3 87
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