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Additionally, the observed weight loss and reduction in systolic blood pressure in the GLP-1RA group may also contribute to the cardiovascular benefits 21,22

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This reduction in calorie intake, and subsequent weight loss, is believed to be caused by a decrease in appetite and cravings and a reduction in cravings for high-fat foods

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The findings show that UA treatment after stroke leads to the protection of brain endothelial cell function, and this beneficial effect is associated with the decrease in circulating levels of VEGF-A and the increase in KLF2 expression