There are of course caveats, since the raw data hasn't been provided, it is not possible to tell whether all individuals showed an increase in C-peptide levels, or whether the average was simply raised by a few individuals (Although the comparable variance at both time of diagnosis and after 12 months, suggests that this is unlikely to be the case)
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The peptide has also demonstrated interactions with the dopaminergic and serotonergic systems, with studies showing that BPC-157 can modulate the effects of dopamine-related agents in animal models and counteract some behavioural and neurochemical consequences of both dopamine agonists and antagonists (Sikiric et al., 2010)
Nevertheless, increasing proof indicates that metformin primarily acts on the gastrointestinal system
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