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And, despite study after study showing no benefit of low-carb diets over low-fat diets for weight loss, many of Lumens recommendations tend to limit carbs, users say

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If the goal is visceral fat reduction specifically, Tesamorelins evidence advantage is real and the cost premium is clinically justified

However, because IGF-1 signaling operates through cellular proliferation pathways also implicated in oncogenic processes, published protocols consistently list active or precancerous conditions as contraindications requiring exclusion from study populations.

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It is usually mild and temporary