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As costs of GLP1s come down, and insurance companies more regularly cover them, a massive new segment of non-coastal, middle-income, and rural Americans - where obesity rates are highest - will enter the market in droves

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During the same period, obesity without T2DM notably increased from 10 to 31%

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While GLP-1R internalization was reduced after dual arrestin siRNA in MIN6B1-SNAP-GLP-1R cells (Supplementary Fig