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In fact, their capability to postpone the progression of the disease further enhances its market penetration

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However, several proposed actions are believed to underlie its physiological effects: 1

The resultant decrease in Ca 2+ uptake due to vitamin D deficiency leads to hypocalcemia leading to excess parathyroid hormone release (referred to as secondary hyperparathyroidism) as a compensatory mechanism

& Reeve, J

[PMC free article: PMC3677810] [PubMed: 20148675] 60