The commonly referenced therapeutic range of 0.25-0.5 mg daily (250-500 mcg) extrapolates from the effective rat dose of approximately 10 mcg/kg body weight
Neurosci Lett 395:103107 Lee M-J, Maliakal P, Chen L, Meng X, Bondoc FY, Prabhu S, Lambert G, Mohr S, Yang CS (2002) Pharmacokinetics of tea catechins after ingestion of green tea and ()-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability
Noom did not immediately respond to requests for comment
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10.1038/sj.ejhg.5201961 342 ValkoM.LeibfritzD.MoncolJ.CroninM
It signals that these peptides have advanced through another layer of scientific and regulatory review, reinforcing the importance of evidence-based evaluation over speculation