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A corresponding role for ferroptosis in human ASCVD is also supported by a genetic analysis of human coronary artery plaques which demonstrated a significant positive association between ferroptosis-related gene expression and ASCVD status 80,81

Cytotoxicity was assessed by measuring lactate dehydrogenase release as previously described [15] and CSE treated cells under conditions tested did not have changes in cell viability that were statistically significantly different from controls and was greater than 85%

A person with a low sense of reward may be attracted to stimulants, and a person with an overly high sense of reward may present as manic