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Caffeine is a non-selective inhibitor of phosphodiesterase (PDE) enzymes involved in the inactivation of cAMP and cyclic guanosine monophosphate (cGMP) with the formation of 5-AMP and 5-GMP

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Biochem Biokhimiia 70:200214 Adam-Vizi V, Chinopoulos C (2006) Bioenergetics and the formation of mitochondrial reactive oxygen species

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