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This is when the bodys repair mechanisms are in full swingbut its also when the skin barrier is at its weakest

In sum, it is worthy to note that lipid peroxidation (LPO) products such as 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA) arise as secondary messengers of oxidative stress, which is often counterbalanced by the cellular antioxidant defense system [133]

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[DOI] [PubMed] [Google Scholar] 80.Cohen H.Y., Lavu S., Bitterman K.J., Hekking B., Imahiyerobo T.A., Miller C., Frye R., Ploegh H., Kessler B.M., Sinclair D.A

The contribution of oxidative stress to necroptosis appears to be highly context-dependent